William Blake and smallpox : the disease in Blake’s London and in Blake’s art

Smallpox was the single most lethal disease in eighteenth-century Britain, accounting for more deaths than any other infectious disease, even plague and cholera. In London, Europe’s largest city by 1700, smallpox increased from 4-6% of all burials in the mid-seventeenth century to over 10% in the third quarter of the eighteenth century, and the frequency of epidemics increased from roughly four-yearly to a biennial cycle over the same period.

Smallpox was an acute, highly contagious, and frequently fatal disease (killing one-seventh to one-quarter of its victims) but conferring lifelong immunity on survivors. It appeared initially as an infrequent epidemic disease affecting all ages, but as the frequency of epidemics increased, a growing proportion of the adult population acquired immunity to the disease, and smallpox was clearly a childhood disease in the London-born population of the eighteenth century, with children under five the main victims. Among those who survived it, morbidity from smallpox was severe in many cases; victims could be left blind or disfigured for life. Few native Londoners would have survived to adulthood without encountering smallpox.

[Indeed, are there any depictions of smallpox in Blake’s work?]